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Activation of the SOS response increases the frequency of small colony variants

BACKGROUND: In Staphylococcus aureus sub-populations of slow-growing cells forming small colony variants (SCVs) are associated with persistent and recurrent infections that are difficult to eradicate with antibiotic therapies. In SCVs that are resistant towards aminoglycosides, mutations have been i...

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Detalles Bibliográficos
Autores principales: Vestergaard, Martin, Paulander, Wilhelm, Ingmer, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672542/
https://www.ncbi.nlm.nih.gov/pubmed/26643526
http://dx.doi.org/10.1186/s13104-015-1735-2