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PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination

The development of vertebrate neurons requires a change in membrane phosphatidylcholine (PC) metabolism. Although PC hydrolysis is essential for enhanced axonal outgrowth mediated by phospholipase D (PLD), less is known about the determinants of PC metabolism on dendritic arborization. We show that...

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Detalles Bibliográficos
Autores principales: Kim, Jun-Dal, Park, Kyung-Eui, Ishida, Junji, Kako, Koichiro, Hamada, Juri, Kani, Shuichi, Takeuchi, Miki, Namiki, Kana, Fukui, Hajime, Fukuhara, Shigetomo, Hibi, Masahiko, Kobayashi, Makoto, Kanaho, Yasunori, Kasuya, Yoshitoshi, Mochizuki, Naoki, Fukamizu, Akiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672763/
https://www.ncbi.nlm.nih.gov/pubmed/26665171
http://dx.doi.org/10.1126/sciadv.1500615