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PRMT8 as a phospholipase regulates Purkinje cell dendritic arborization and motor coordination
The development of vertebrate neurons requires a change in membrane phosphatidylcholine (PC) metabolism. Although PC hydrolysis is essential for enhanced axonal outgrowth mediated by phospholipase D (PLD), less is known about the determinants of PC metabolism on dendritic arborization. We show that...
Autores principales: | Kim, Jun-Dal, Park, Kyung-Eui, Ishida, Junji, Kako, Koichiro, Hamada, Juri, Kani, Shuichi, Takeuchi, Miki, Namiki, Kana, Fukui, Hajime, Fukuhara, Shigetomo, Hibi, Masahiko, Kobayashi, Makoto, Kanaho, Yasunori, Kasuya, Yoshitoshi, Mochizuki, Naoki, Fukamizu, Akiyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672763/ https://www.ncbi.nlm.nih.gov/pubmed/26665171 http://dx.doi.org/10.1126/sciadv.1500615 |
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