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Compound Heterozygosity for Y Box Proteins Causes Sterility Due to Loss of Translational Repression

The Y-box proteins YBX2 and YBX3 bind RNA and DNA and are required for metazoan development and fertility. However, possible functional redundancy between YBX2 and YBX3 has prevented elucidation of their molecular function as RNA masking proteins and identification of their target RNAs. To investiga...

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Detalles Bibliográficos
Autores principales: Snyder, Elizabeth, Soundararajan, Ramani, Sharma, Manju, Dearth, Andrea, Smith, Benjamin, Braun, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672889/
https://www.ncbi.nlm.nih.gov/pubmed/26646932
http://dx.doi.org/10.1371/journal.pgen.1005690