Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells

BACKGROUND: Recent clinical trials using c-kit(+) human cardiac stem cells (CSCs) demonstrated promising results in increasing cardiac function and improving quality of life. However, CSC efficiency is low, likely due to limited cell survival and engraftment after transplantation. The Rho-associated...

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Detalles Bibliográficos
Autores principales: Kan, Lijuan, Smith, Aubrie, Chen, Miao, Ledford, Benjamin T., Fan, Huimin, Liu, Zhongmin, He, Jia-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672899/
https://www.ncbi.nlm.nih.gov/pubmed/26645568
http://dx.doi.org/10.1371/journal.pone.0144513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672899/
https://www.ncbi.nlm.nih.gov/pubmed/26645568
http://dx.doi.org/10.1371/journal.pone.0144513

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