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Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells
BACKGROUND: Recent clinical trials using c-kit(+) human cardiac stem cells (CSCs) demonstrated promising results in increasing cardiac function and improving quality of life. However, CSC efficiency is low, likely due to limited cell survival and engraftment after transplantation. The Rho-associated...
Autores principales: | Kan, Lijuan, Smith, Aubrie, Chen, Miao, Ledford, Benjamin T., Fan, Huimin, Liu, Zhongmin, He, Jia-Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672899/ https://www.ncbi.nlm.nih.gov/pubmed/26645568 http://dx.doi.org/10.1371/journal.pone.0144513 |
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