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MASP-1 Induced Clotting – The First Model of Prothrombin Activation by MASP-1

Mannan-binding lectin-associated serine protease-1 (MASP-1), a protein of the complement lectin pathway, resembles thrombin in terms of structural features and substrate specificity. Due to its interplay with several coagulation factors, it has the ability to induce fibrin clot formation independent...

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Detalles Bibliográficos
Autores principales: Jenny, Lorenz, Dobó, József, Gál, Péter, Schroeder, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672900/
https://www.ncbi.nlm.nih.gov/pubmed/26645987
http://dx.doi.org/10.1371/journal.pone.0144633