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Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer

Omics data integration is becoming necessary to investigate the genomic mechanisms involved in complex diseases. During the integration process, many challenges arise such as data heterogeneity, the smaller number of individuals in comparison to the number of parameters, multicollinearity, and inter...

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Detalles Bibliográficos
Autores principales: Pineda, Silvia, Real, Francisco X., Kogevinas, Manolis, Carrato, Alfredo, Chanock, Stephen J., Malats, Núria, Van Steen, Kristel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672920/
https://www.ncbi.nlm.nih.gov/pubmed/26646822
http://dx.doi.org/10.1371/journal.pgen.1005689