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Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer
Omics data integration is becoming necessary to investigate the genomic mechanisms involved in complex diseases. During the integration process, many challenges arise such as data heterogeneity, the smaller number of individuals in comparison to the number of parameters, multicollinearity, and inter...
Autores principales: | Pineda, Silvia, Real, Francisco X., Kogevinas, Manolis, Carrato, Alfredo, Chanock, Stephen J., Malats, Núria, Van Steen, Kristel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672920/ https://www.ncbi.nlm.nih.gov/pubmed/26646822 http://dx.doi.org/10.1371/journal.pgen.1005689 |
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