Pyrroloquinoline Quinone Resists Denervation-Induced Skeletal Muscle Atrophy by Activating PGC-1α and Integrating Mitochondrial Electron Transport Chain Complexes

Denervation-mediated skeletal muscle atrophy results from the loss of electric stimulation and leads to protein degradation, which is critically regulated by the well-confirmed transcriptional co-activator peroxisome proliferator co-activator 1 alpha (PGC-1α). No adequate treatments of muscle wastin...

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Detalles Bibliográficos
Autores principales: Kuo, Yung-Ting, Shih, Ping-Hsiao, Kao, Shu-Huei, Yeh, Geng-Chang, Lee, Horng-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672922/
https://www.ncbi.nlm.nih.gov/pubmed/26646764
http://dx.doi.org/10.1371/journal.pone.0143600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672922/
https://www.ncbi.nlm.nih.gov/pubmed/26646764
http://dx.doi.org/10.1371/journal.pone.0143600

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