Identification of Major Signaling Pathways in Prion Disease Progression Using Network Analysis

Prion diseases are transmissible neurodegenerative diseases that arise due to conformational change of normal, cellular prion protein (PrP(C)) to protease-resistant isofrom (rPrP(Sc)). Deposition of misfolded Prp(Sc) proteins leads to an alteration of many signaling pathways that includes immunologi...

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Detalles Bibliográficos
Autores principales: Newaz, Khalique, Sriram, K., Bera, Debajyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672924/
https://www.ncbi.nlm.nih.gov/pubmed/26646948
http://dx.doi.org/10.1371/journal.pone.0144389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672924/
https://www.ncbi.nlm.nih.gov/pubmed/26646948
http://dx.doi.org/10.1371/journal.pone.0144389

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