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The hypotensive effect of acute and chronic AMP-activated protein kinase activation in normal and hyperlipidemic mice
AMP-activated protein kinase (AMPK) is present in the arterial wall and is activated in response to cellular stressors that raise AMP relative to ADP/ATP. Activation of AMPK in vivo lowers blood pressure but the influence of hyperlipidemia on this response has not been studied. ApoE(−/−) mice on hig...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673085/ https://www.ncbi.nlm.nih.gov/pubmed/26196300 http://dx.doi.org/10.1016/j.vph.2015.07.010 |