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The hypotensive effect of acute and chronic AMP-activated protein kinase activation in normal and hyperlipidemic mice

AMP-activated protein kinase (AMPK) is present in the arterial wall and is activated in response to cellular stressors that raise AMP relative to ADP/ATP. Activation of AMPK in vivo lowers blood pressure but the influence of hyperlipidemia on this response has not been studied. ApoE(−/−) mice on hig...

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Detalles Bibliográficos
Autores principales: Greig, Fiona H., Ewart, Marie-Ann, McNaughton, Eilidh, Cooney, Josephine, Spickett, Corinne M., Kennedy, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673085/
https://www.ncbi.nlm.nih.gov/pubmed/26196300
http://dx.doi.org/10.1016/j.vph.2015.07.010