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Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial

BACKGROUND: Maternal obesity is associated with increased birthweight, and obesity and premature mortality in adult offspring. The mechanism by which maternal obesity leads to these outcomes is not well understood, but maternal hyperglycaemia and insulin resistance are both implicated. We aimed to e...

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Detalles Bibliográficos
Autores principales: Chiswick, Carolyn, Reynolds, Rebecca M, Denison, Fiona, Drake, Amanda J, Forbes, Shareen, Newby, David E, Walker, Brian R, Quenby, Siobhan, Wray, Susan, Weeks, Andrew, Lashen, Hany, Rodriguez, Aryelly, Murray, Gordon, Whyte, Sonia, Norman, Jane E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Lancet, Diabetes & Endocrinology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673088/
https://www.ncbi.nlm.nih.gov/pubmed/26165398
http://dx.doi.org/10.1016/S2213-8587(15)00219-3