Perifosine as a potential novel anti-telomerase therapy

Most tumors circumvent telomere-length imposed replicative limits through expression of telomerase, the reverse transcriptase that maintains telomere length. Substantial evidence that AKT activity is required for telomerase activity exists, indicating that AKT inhibitors may also function as telomer...

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Detalles Bibliográficos
Autores principales: Holohan, Brody, Hagiopian, Moriah M., Lai, Tsung-Po, Huang, Ejun, Friedman, Daphne R., Wright, Woodring E., Shay, Jerry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673128/
https://www.ncbi.nlm.nih.gov/pubmed/26307677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673128/
https://www.ncbi.nlm.nih.gov/pubmed/26307677

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