In vivo hematopoietic Myc activation directs a transcriptional signature in endothelial cells within the bone marrow microenvironment

Cancer pathogenesis involves tumor-intrinsic genomic aberrations and tumor-cell extrinsic mechanisms such as failure of immunosurveillance and structural and functional changes in the microenvironment. Using Myc as a model oncogene we established a conditional mouse bone marrow transduction/transpla...

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Detalles Bibliográficos
Autores principales: Franke, Katharina, Vilne, Baiba, da Costa, Olivia Prazeres, Rudelius, Martina, Peschel, Christian, Oostendorp, Robert A.J., Keller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673129/
https://www.ncbi.nlm.nih.gov/pubmed/26308666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673129/
https://www.ncbi.nlm.nih.gov/pubmed/26308666

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