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In vivo hematopoietic Myc activation directs a transcriptional signature in endothelial cells within the bone marrow microenvironment

Cancer pathogenesis involves tumor-intrinsic genomic aberrations and tumor-cell extrinsic mechanisms such as failure of immunosurveillance and structural and functional changes in the microenvironment. Using Myc as a model oncogene we established a conditional mouse bone marrow transduction/transpla...

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Detalles Bibliográficos
Autores principales:	Franke, Katharina, Vilne, Baiba, da Costa, Olivia Prazeres, Rudelius, Martina, Peschel, Christian, Oostendorp, Robert A.J., Keller, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673129/ https://www.ncbi.nlm.nih.gov/pubmed/26308666

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