DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers

Stratification of oestrogen receptor (ER) negative and triple negative breast cancers (TNBCs) is urgently needed. In the current study, a cohort of 880 ER- (including 635 TNBCs) was immuno-profiled for a panel of DNA repair proteins including: Pol β, FEN1, APE1, XRCC1, SMUG1, PARP1, BRCA1, ATR, ATM,...

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Detalles Bibliográficos
Autores principales: Abdel-Fatah, Tarek M.A., Arora, Arvind, Moseley, Paul M., Perry, Christina, Rakha, Emad A., Green, Andrew R., Chan, Stephen Y.T., Ellis, Ian O., Madhusudan, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673139/
https://www.ncbi.nlm.nih.gov/pubmed/26267318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673139/
https://www.ncbi.nlm.nih.gov/pubmed/26267318

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