Genome-wide mutation profiles of colorectal tumors and associated liver metastases at the exome and transcriptome levels

To characterize the mutation profiles of colorectal cancer (CRC) primary tumors (PTs) and liver metastases (CLMs), we performed both whole-exome and RNA sequencing. Ten significantly mutated genes, including BMI1, CARD11, and NRG1, were found in 34 CRCs with CLMs. We defined three mutation classes (...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Byungho, Mun, Jihyeob, Kim, Jeong-Hwan, Kim, Chan Wook, Roh, Seon Ae, Cho, Dong-Hyung, Kim, Yong Sung, Kim, Seon-Young, Kim, Jin Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673155/
https://www.ncbi.nlm.nih.gov/pubmed/26109429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673155/
https://www.ncbi.nlm.nih.gov/pubmed/26109429

Ejemplares similares