Cargando…

Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response

Aims: Recent studies have observed that cells from high-grade glial tumors are capable of assuming an endothelial phenotype and genotype, a process termed ‘vasculogenic mimicry’ (VM). Here we model and manipulate VM in dynamic 3-dimensional (3D) glioma cultures. Methods: The Rotary Cell Culture Syst...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Stuart J., Ward, Jennifer H., Tan, Christopher, Grundy, Richard G., Rahman, Ruman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673156/
https://www.ncbi.nlm.nih.gov/pubmed/26203665