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Intact LKB1 activity is required for survival of dormant ovarian cancer spheroids

Metastatic epithelial ovarian cancer (EOC) cells can form multicellular spheroids while in suspension and disperse directly throughout the peritoneum to seed secondary lesions. There is growing evidence that EOC spheroids are key mediators of metastasis, and they use specific intracellular signallin...

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Detalles Bibliográficos
Autores principales: Peart, Teresa, Valdes, Yudith Ramos, Correa, Rohann J. M., Fazio, Elena, Bertrand, Monique, McGee, Jacob, Préfontaine, Michel, Sugimoto, Akira, DiMattia, Gabriel E., Shepherd, Trevor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673173/
https://www.ncbi.nlm.nih.gov/pubmed/26068970