Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3

Protein arginine methyltransferases (PRMTs) plays critical roles in cancer. PRMT5 has been implicated in several types of tumors. However, the role of PRMT5 in cancer development remains to be fully elucidated. Here, we provide evidence that PRMT5 is overexpressed in colorectal cancer (CRC) cells an...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Baolai, Dong, Shuhong, Zhu, Ruiming, Hu, Chunyan, Hou, Jing, Li, Yan, Zhao, Qian, Shao, Xue, Bu, Qian, Li, Hongyu, Wu, Yongjie, Cen, Xiaobo, Zhao, Yinglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673200/
https://www.ncbi.nlm.nih.gov/pubmed/26078354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673200/
https://www.ncbi.nlm.nih.gov/pubmed/26078354

Ejemplares similares