Next-generation sequencing of FLT3 internal tandem duplications for minimal residual disease monitoring in acute myeloid leukemia

Minimal Residual Disease (MRD) detection can be used for early intervention in relapse, risk stratification, and treatment guidance. FLT3 ITD is the most common mutation found in AML patients with normal karyotype. We evaluated the feasibility of NGS with high coverage (up to 2.4.10(6) PE fragments)...

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Detalles Bibliográficos
Autores principales: Bibault, Jean-Emmanuel, Figeac, Martin, Hélevaut, Nathalie, Rodriguez, Céline, Quief, Sabine, Sebda, Shéhérazade, Renneville, Aline, Nibourel, Olivier, Rousselot, Philippe, Gruson, Bérengère, Dombret, Hervé, Castaigne, Sylvie, Preudhomme, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673201/
https://www.ncbi.nlm.nih.gov/pubmed/26078355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673201/
https://www.ncbi.nlm.nih.gov/pubmed/26078355

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