Small molecule/ML327 mediated transcriptional de-repression of E-cadherin and inhibition of epithelial-to-mesenchymal transition

Transcriptional repression of E-cadherin is a hallmark of Epithelial-to-Mesenchymal Transition (EMT) and is associated with cancer cell invasion and metastasis. Understanding the mechanisms underlying E-cadherin repression during EMT may provide insights into the development of novel targeted therap...

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Detalles Bibliográficos
Autores principales: An, Hanbing, Stoops, Sydney L., Deane, Natasha G., Zhu, Jing, Zi, Jinghuan, Weaver, Connie, Waterson, Alex G., Zijlstra, Andries, Lindsley, Craig W., Beauchamp, Robert Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673210/
https://www.ncbi.nlm.nih.gov/pubmed/26082441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673210/
https://www.ncbi.nlm.nih.gov/pubmed/26082441

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