Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy

Aneuploidy is a common feature of cancer, with human solid tumour cells typically harbouring abnormal chromosome complements. The aneuploidy observed in cancer is often caused by a chromosome instability phenotype, resulting in genomic heterogeneity. However, the role aneuploidy and chromosome insta...

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Detalles Bibliográficos
Autores principales: Bennett, Ailsa, Bechi, Beatrice, Tighe, Anthony, Thompson, Sarah, Procter, David J., Taylor, Stephen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Chromosome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673239/
https://www.ncbi.nlm.nih.gov/pubmed/26320186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673239/
https://www.ncbi.nlm.nih.gov/pubmed/26320186

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