Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface

α-L-fucosidase 1 (FUCA1) is a lysosomal enzyme that catalyzes the hydrolytic cleavage of the terminal fucose residue in breast cancer cells. FUCA1 mRNA levels were detected by real-time PCR, and there was a greater than 139-fold increase in FUCA1 mRNA expression in breast tumor samples compared with...

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Detalles Bibliográficos
Autores principales: Cheng, Tzu-Chun, Tu, Shih-Hsin, Chen, Li-Ching, Chen, Ming-Yao, Chen, Wen-Ye, Lin, Yen-Kuang, Ho, Chi-Tang, Lin, Shyr-Yi, Wu, Chih-Hsiung, Ho, Yuan-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673265/
https://www.ncbi.nlm.nih.gov/pubmed/26204487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673265/
https://www.ncbi.nlm.nih.gov/pubmed/26204487

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