NPM1 activates metabolic changes by inhibiting FBP1 while promoting the tumorigenicity of pancreatic cancer cells

The nucleophosmin (NPM1) activates cancer development and progression in many malignant tumors. However, the regulatory role and underlying mechanisms of NPM1 in pancreatic cancer are unknown. In this study, we showed that NPM1 was up-regulated in PDAC, which indicated a poor prognosis. We also iden...

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Detalles Bibliográficos
Autores principales: Zhu, Yi, Shi, Minmin, Chen, Hao, Gu, Jiangning, Zhang, Jiaqiang, Shen, Baiyong, Deng, Xiaxing, Xie, Junjie, Zhan, Xi, Peng, Chenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673277/
https://www.ncbi.nlm.nih.gov/pubmed/26068981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673277/
https://www.ncbi.nlm.nih.gov/pubmed/26068981

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