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Nuclear translocation of fibroblast growth factor-2 (FGF2) is regulated by Karyopherin-β2 and Ran GTPase in human glioblastoma cells

Human glioblastoma multiforme (GBM) is the most malignant tumor of the central nervous system (CNS). Fibroblast growth factor-2 (FGF2) belongs to the FGF superfamily and functions as a potential oncoprotein in GBM. FGF2 has low molecular weight (18K) and high molecular weight (HMW) isoforms. Nuclear...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Yang, Lijun, Shi, Lin, Li, Qian, Zhang, Gengshen, Wu, Jianliang, Zheng, Jun, Jiao, Baohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673279/
https://www.ncbi.nlm.nih.gov/pubmed/26056081