Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib

The multi-kinase inhibitor sorafenib is now used as standard therapy for advanced hepatocellular carcinoma (HCC). Predictive biomarkers of response to sorafenib are thus necessary. The purpose of this study was to assess the feasibility of using targeted DNA and RNA sequencing to elucidate candidate...

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Detalles Bibliográficos
Autores principales: Sakai, Kazuko, Takeda, Haruhiko, Nishijima, Norihiro, Orito, Etsuro, Joko, Kouji, Uchida, Yasushi, Izumi, Namiki, Nishio, Kazuto, Osaki, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673292/
https://www.ncbi.nlm.nih.gov/pubmed/26046304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673292/
https://www.ncbi.nlm.nih.gov/pubmed/26046304

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