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Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels

The adhesion properties of cells are involved in tumor metastasis. Although KRS at the plasma membrane is shown important for cancer metastasis, additionally to canonical roles of cytosolic KRS in protein translation, how KRS and its downstream effectors promote the metastatic migration remains unex...

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Detalles Bibliográficos
Autores principales: Nam, Seo Hee, Kim, Doyeun, Lee, Mi-Sook, Lee, Doohyung, Kwak, Tae Kyoung, Kang, Minkyung, Ryu, Jihye, Kim, Hye-Jin, Song, Haeng Eun, Choi, Jungeun, Lee, Gyu-Ho, Kim, Sang-Yeob, Park, Song Hwa, Kim, Dae Gyu, Kwon, Nam Hoon, Kim, Tai Young, Thiery, Jean Paul, Kim, Sunghoon, Lee, Jung Weon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673294/
https://www.ncbi.nlm.nih.gov/pubmed/26091349