Epigenetic and oncogenic regulation of SLC16A7 (MCT2) results in protein over-expression, impacting on signalling and cellular phenotypes in prostate cancer

Monocarboxylate Transporter 2 (MCT2) is a major pyruvate transporter encoded by the SLC16A7 gene. Recent studies pointed to a consistent overexpression of MCT2 in prostate cancer (PCa) suggesting MCT2 as a putative biomarker and molecular target. Despite the importance of this observation the mechan...

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Detalles Bibliográficos
Autores principales: Pertega-Gomes, Nelma, Vizcaino, Jose R., Felisbino, Sergio, Warren, Anne Y., Shaw, Greg, Kay, Jonathan, Whitaker, Hayley, Lynch, Andy G., Fryer, Lee, Neal, David E., Massie, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673295/
https://www.ncbi.nlm.nih.gov/pubmed/26035357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673295/
https://www.ncbi.nlm.nih.gov/pubmed/26035357

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