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Design and Synthesis of a Novel Cationic Peptide with Potent and Broad-Spectrum Antimicrobial Activity

Antibacterial and antifungal peptides have increasingly been used to combat the antibiotic-resistant microbes in recent years. KW-13, a novel cationic α-helical antibacterial peptide consisting of 13 amino acid residues, was designed and chemically synthesized. The peptide has a net charge of +6 wit...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Ping, Chen, Ya-Hui, Ming, Xin, Kong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673326/
https://www.ncbi.nlm.nih.gov/pubmed/26688811
http://dx.doi.org/10.1155/2015/578764