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N-Acetylneuraminic Acid Supplementation Prevents High Fat Diet-Induced Insulin Resistance in Rats through Transcriptional and Nontranscriptional Mechanisms

N-Acetylneuraminic acid (Neu5Ac) is a biomarker of cardiometabolic diseases. In the present study, we tested the hypothesis that dietary Neu5Ac may improve cardiometabolic indices. A high fat diet (HFD) + Neu5Ac (50 or 400 mg/kg BW/day) was fed to rats and compared with HFD + simvastatin (10 mg/kg B...

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Detalles Bibliográficos
Autores principales: Yida, Zhang, Imam, Mustapha Umar, Ismail, Maznah, Ismail, Norsharina, Azmi, Nur Hanisah, Wong, Waiteng, Altine Adamu, Hadiza, Md Zamri, Nur Diyana, Ideris, Aini, Abdullah, Maizaton Atmadini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673348/
https://www.ncbi.nlm.nih.gov/pubmed/26688813
http://dx.doi.org/10.1155/2015/602313