MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction

Aims. miR-208a is associated with adverse outcomes in several cardiac pathologies known to have increased apoptosis, including myocardial infarction (MI). We investigated if miR-208a has proapoptotic effects on ischemic cardiomyocytes and if its silencing has therapeutic benefits in MI. Methods and...

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Detalles Bibliográficos
Autores principales: Tony, Hasahya, Meng, Kai, Wu, Bangwei, Yu, Aijia, Zeng, Qiutang, Yu, Kunwu, Zhong, Yucheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673358/
https://www.ncbi.nlm.nih.gov/pubmed/26688617
http://dx.doi.org/10.1155/2015/479123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673358/
https://www.ncbi.nlm.nih.gov/pubmed/26688617
http://dx.doi.org/10.1155/2015/479123

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