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Blockade of Retinol Metabolism Protects T Cell-Induced Hepatitis by Increasing Migration of Regulatory T Cells

Retinols are metabolized into retinoic acids by alcohol dehydrogenase (ADH) and retinaldehyde dehydrogenase (Raldh). However, their roles have yet to be clarified in hepatitis despite enriched retinols in hepatic stellate cells (HSCs). Therefore, we investigated the effects of retinols on Concanaval...

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Detalles Bibliográficos
Autores principales: Lee, Young-Sun, Yi, Hyon-Seung, Suh, Yang-Gun, Byun, Jin-Seok, Eun, Hyuk Soo, Kim, So Yeon, Seo, Wonhyo, Jeong, Jong-Min, Choi, Won-Mook, Kim, Myung-Ho, Kim, Ji Hoon, Park, Keun-Gyu, Jeong, Won-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673415/
https://www.ncbi.nlm.nih.gov/pubmed/26537191
http://dx.doi.org/10.14348/molcells.2015.0218