SMARCAL1 Negatively Regulates C-Myc Transcription By Altering The Conformation Of The Promoter Region

SMARCAL1, a member of the SWI2/SNF2 protein family, stabilizes replication forks during DNA damage. In this manuscript, we provide the first evidence that SMARCAL1 is also a transcriptional co-regulator modulating the expression of c-Myc, a transcription factor that regulates 10–15% genes in the hum...

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Detalles Bibliográficos
Autores principales: Sharma, Tapan, Bansal, Ritu, Haokip, Dominic Thangminlen, Goel, Isha, Muthuswami, Rohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673416/
https://www.ncbi.nlm.nih.gov/pubmed/26648259
http://dx.doi.org/10.1038/srep17910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673416/
https://www.ncbi.nlm.nih.gov/pubmed/26648259
http://dx.doi.org/10.1038/srep17910

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