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DNA methylation is stable during replication and cell cycle arrest

DNA methylation is an epigenetic modification with important functions in development. Large-scale loss of DNA methylation is a hallmark of cancer. Recent work has identified large genomic blocks of hypomethylation associated with cancer, EBV transformation and replicative senescence, all of which c...

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Detalles Bibliográficos
Autores principales: Vandiver, Amy R., Idrizi, Adrian, Rizzardi, Lindsay, Feinberg, Andrew P., Hansen, Kasper D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673417/
https://www.ncbi.nlm.nih.gov/pubmed/26648411
http://dx.doi.org/10.1038/srep17911