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Single Cell Dynamics Causes Pareto-Like Effect in Stimulated T Cell Populations

Cell fate choice during the process of differentiation may obey to deterministic or stochastic rules. In order to discriminate between these two strategies we used time-lapse microscopy of individual murine CD4 + T cells that allows investigating the dynamics of proliferation and fate commitment. We...

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Detalles Bibliográficos
Autores principales: Cosette, Jérémie, Moussy, Alice, Onodi, Fanny, Auffret-Cariou, Adrien, Neildez-Nguyen, Thi My Anh, Paldi, Andras, Stockholm, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673432/
https://www.ncbi.nlm.nih.gov/pubmed/26648396
http://dx.doi.org/10.1038/srep17756