Development of synthetic anti-cyclic citrullinated peptide antibody and its arthritogenic role

This study was undertaken to develop a novel anti-citrullinated peptide antibody (ACPA) and to investigate its arthritogenicity in a collagen-induced arthritis (CIA) model. The novel ACPA, 12G1, was developed by injecting cyclic citrullinated antigen in mice and subsequently hybridizing the B cells...

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Detalles Bibliográficos
Autores principales: Kim, Youngkyun, Lee, Jennifer, Jung, Hyerin, Yi, Hyoju, Rim, Yeri Alice, Jung, Seung Min, Ju, Ji Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673436/
https://www.ncbi.nlm.nih.gov/pubmed/26682058
http://dx.doi.org/10.1038/cti.2015.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673436/
https://www.ncbi.nlm.nih.gov/pubmed/26682058
http://dx.doi.org/10.1038/cti.2015.24

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