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Development of synthetic anti-cyclic citrullinated peptide antibody and its arthritogenic role
This study was undertaken to develop a novel anti-citrullinated peptide antibody (ACPA) and to investigate its arthritogenicity in a collagen-induced arthritis (CIA) model. The novel ACPA, 12G1, was developed by injecting cyclic citrullinated antigen in mice and subsequently hybridizing the B cells...
Autores principales: | Kim, Youngkyun, Lee, Jennifer, Jung, Hyerin, Yi, Hyoju, Rim, Yeri Alice, Jung, Seung Min, Ju, Ji Hyeon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673436/ https://www.ncbi.nlm.nih.gov/pubmed/26682058 http://dx.doi.org/10.1038/cti.2015.24 |
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