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Rac-mediated actin remodeling and myosin II are involved in K(ATP) channel trafficking in pancreatic β-cells

AMP-activated protein kinase (AMPK) is a metabolic sensor activated during metabolic stress and it regulates various enzymes and cellular processes to maintain metabolic homeostasis. We previously reported that activation of AMPK by glucose deprivation (GD) and leptin increases K(ATP) currents by in...

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Detalles Bibliográficos
Autores principales: Han, Young-Eun, Lim, Ajin, Park, Sun-Hyun, Chang, Sunghoe, Lee, Suk-Ho, Ho, Won-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673475/
https://www.ncbi.nlm.nih.gov/pubmed/26471000
http://dx.doi.org/10.1038/emm.2015.72