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PH motifs in PAR(1&2) endow breast cancer growth

Although emerging roles of protease-activated receptor(1&2) (PAR(1&2)) in cancer are recognized, their underlying signalling events are poorly understood. Here we show signal-binding motifs in PAR(1&2) that are critical for breast cancer growth. This occurs via the association of the ple...

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Detalles Bibliográficos
Autores principales: Kancharla, A., Maoz, M., Jaber, M., Agranovich, D., Peretz, T., Grisaru-Granovsky, S., Uziely, B., Bar-Shavit, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673491/
https://www.ncbi.nlm.nih.gov/pubmed/26600192
http://dx.doi.org/10.1038/ncomms9853