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Rescue of neonatal cardiac dysfunction in mice by administration of cardiac progenitor cells in utero

Striated preferentially expressed gene (Speg) is a member of the myosin light chain kinase family. We previously showed that disruption of the Speg gene locus in mice leads to a dilated cardiomyopathy with immature-appearing cardiomyocytes. Here we show that cardiomyopathy of Speg(−/−) mice arises a...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoli, Hall, Sean R. R., Wang, Zhihong, Huang, He, Ghanta, Sailaja, Di Sante, Moises, Leri, Annarosa, Anversa, Piero, Perrella, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673493/
https://www.ncbi.nlm.nih.gov/pubmed/26593099
http://dx.doi.org/10.1038/ncomms9825