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Histone H1-mediated epigenetic regulation controls germline stem cell self-renewal by modulating H4K16 acetylation
Epigenetics plays critical roles in controlling stem cell self-renewal and differentiation. Histone H1 is one of the most critical chromatin regulators, but its role in adult stem cell regulation remains unclear. Here we report that H1 is intrinsically required in the regulation of germline stem cel...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673494/ https://www.ncbi.nlm.nih.gov/pubmed/26581759 http://dx.doi.org/10.1038/ncomms9856 |