Integrative genomic mining for enzyme function to enable engineering of a non-natural biosynthetic pathway

The ability to biosynthetically produce chemicals beyond what is commonly found in Nature requires the discovery of novel enzyme function. Here we utilize two approaches to discover enzymes that enable specific production of longer-chain (C(5)–C(8)) alcohols from sugar. The first approach combines b...

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Detalles Bibliográficos
Autores principales: Mak, Wai Shun, Tran, Stephen, Marcheschi, Ryan, Bertolani, Steve, Thompson, James, Baker, David, Liao, James C., Siegel, Justin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673503/
https://www.ncbi.nlm.nih.gov/pubmed/26598135
http://dx.doi.org/10.1038/ncomms10005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673503/
https://www.ncbi.nlm.nih.gov/pubmed/26598135
http://dx.doi.org/10.1038/ncomms10005

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