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Redistribution of Kv1 and Kv7 enhances neuronal excitability during structural axon initial segment plasticity

Structural plasticity of the axon initial segment (AIS), the trigger zone of neurons, is a powerful means for regulating neuronal activity. Here, we show that AIS plasticity is not limited to structural changes; it also occurs as changes in ion-channel expression, which substantially augments the ef...

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Detalles Bibliográficos
Autores principales: Kuba, Hiroshi, Yamada, Rei, Ishiguro, Go, Adachi, Ryota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673506/
https://www.ncbi.nlm.nih.gov/pubmed/26581625
http://dx.doi.org/10.1038/ncomms9815