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Combined immunomodulator and antimicrobial therapy eliminates polymicrobial sepsis and modulates cytokine production in combined injured mice

Purpose: A combination therapy for combined injury (CI) using a non-specific immunomodulator, synthetic trehalose dicorynomycolate and monophosphoryl lipid A (STDCM-MPL), was evaluated to augment oral antimicrobial agents, levofloxacin (LVX) and amoxicillin (AMX), to eliminate endogenous sepsis and...

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Detalles Bibliográficos
Autores principales: Elliott, Thomas B., Bolduc, David L., Ledney, G. David, Kiang, Juliann G., Fatanmi, Oluseyi O., Wise, Stephen Y., Romaine, Patricia L. P., Newman, Victoria L., Singh, Vijay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673550/
https://www.ncbi.nlm.nih.gov/pubmed/25994812
http://dx.doi.org/10.3109/09553002.2015.1054526