Energetics of Endotoxin Recognition in the Toll-Like Receptor 4 Innate Immune Response

Bacterial outer membrane lipopolysaccharide (LPS) potently stimulates the mammalian innate immune system, and can lead to sepsis, the primary cause of death from infections. LPS is sensed by Toll-like receptor 4 (TLR4) in complex with its lipid-binding coreceptor MD-2, but subtle structural variatio...

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Detalles Bibliográficos
Autores principales: Paramo, Teresa, Tomasio, Susana M., Irvine, Kate L., Bryant, Clare E., Bond, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673606/
https://www.ncbi.nlm.nih.gov/pubmed/26647780
http://dx.doi.org/10.1038/srep17997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673606/
https://www.ncbi.nlm.nih.gov/pubmed/26647780
http://dx.doi.org/10.1038/srep17997

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