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A simple feature construction method for predicting upstream/downstream signal flow in human protein-protein interaction networks

Signaling pathways play important roles in understanding the underlying mechanism of cell growth, cell apoptosis, organismal development and pathways-aberrant diseases. Protein-protein interaction (PPI) networks are commonly-used infrastructure to infer signaling pathways. However, PPI networks gene...

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Detalles Bibliográficos
Autores principales: Mei, Suyu, Zhu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673612/
https://www.ncbi.nlm.nih.gov/pubmed/26648121
http://dx.doi.org/10.1038/srep17983