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A simple feature construction method for predicting upstream/downstream signal flow in human protein-protein interaction networks
Signaling pathways play important roles in understanding the underlying mechanism of cell growth, cell apoptosis, organismal development and pathways-aberrant diseases. Protein-protein interaction (PPI) networks are commonly-used infrastructure to infer signaling pathways. However, PPI networks gene...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673612/ https://www.ncbi.nlm.nih.gov/pubmed/26648121 http://dx.doi.org/10.1038/srep17983 |