Loss of Jagged1 in renin progenitors leads to focal kidney fibrosis

The Notch signaling pathway is required to maintain renin expression within juxtaglomerular (JG) cells. However, the specific ligand which activates Notch signaling in renin-expressing cells remains undefined. In this study, we found that among all Notch ligands, Jagged1 is differentially expressed...

Descripción completa

Detalles Bibliográficos
Autores principales: Belyea, Brian C, Xu, Fang, Sequeira-Lopez, Maria Luisa S, Ariel Gomez, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673620/
https://www.ncbi.nlm.nih.gov/pubmed/26537340
http://dx.doi.org/10.14814/phy2.12544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673620/
https://www.ncbi.nlm.nih.gov/pubmed/26537340
http://dx.doi.org/10.14814/phy2.12544

Ejemplares similares