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A cell size- and cell cycle-aware stochastic model for predicting time-dynamic gene network activity in individual cells
BACKGROUND: Despite the development of various modeling approaches to predict gene network activity, a time dynamic stochastic model taking into account real-time changes in cell volume and cell cycle stages is still missing. RESULTS: Here we present a stochastic single-cell model that can be applie...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673848/ https://www.ncbi.nlm.nih.gov/pubmed/26646617 http://dx.doi.org/10.1186/s12918-015-0240-5 |